Randomized trial of spatially targeted malaria control to virtually eliminate malaria in areas of low and patchy transmission in Senegal

Randomized trial of spatially targeted malaria control to virtually eliminate malaria in areas of low and patchy transmission in Senegal

Objectives

The purpose of this trial is to evaluate the extent to which a targeted malaria control strategy combining vector control with indoor residual spraying (IRS) and chemotherapy (MSAT or MDA), delivered by district health staff to villages reporting clinical cases, can virtually eliminate malaria, in an area in central Senegal where malaria incidence is very low and patchy. Secondly we will determine whether, as part of this strategy, chemotherapy should be delivered to all members of targeted communities or only those who have been tested and are known to be infected.

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Partner(s)

Abstract

In central Senegal where malaria incidence is low and good access to diagnosis and treatment is provided through health facilities and community case management, malaria can be virtually eliminated by a strategy of targetted IRS and MSAT (mass screening with RDT and treatment with ACT), with target areas defined from RDT-confirmed incident cases of clinical malaria detected by health workers. 

A trial of targetted control to eliminate malaria in Central Senegal

Key facts

  • Funding information
    Global Public Health Trials Scheme
    Country
    • Senegal

MESA tags

  • Methodology
    Entomology, Operational research
    Theme(s)
    Drug-based strategies, Elimination strategies, Impact of interventions, Tools for elimination