A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P. falciparum malaria

A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P. falciparum malaria

Objectives

The aim of this study is to provide data on pharmacokinetic profile, safety and efficacy of this new paediatric formulation and compare it with the crushed film coated tablet in infant patients (6 to ≤12 months of age) suffering from uncomplicated Plasmodium falciparum malaria.

Furthermore, a Pharmacokinetic/Pharmacodynamic(PK/PD) modelling will be built up to establish PK/PD relationship in adult and paediatric populations.

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Partner(s)

A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P. Falciparum Malaria

Key facts

  • Dates
    Nov 2013 to Jul 2015
    Country
    • Congo, the Democratic Republic of the
    • Tanzania, United Republic of
    • Mozambique
    • Burkina Faso
    • Gambia

MESA tags

  • Methodology
    Operational research, Product development & clinical research
    Theme(s)
    Impact of interventions, Vulnerable populations