Optimization, standardization and development of a new functional assay for the evaluation of malaria immunity using the antibody dependant respiratory burst (ADRB) of cell effectors detected by chemiluminescence
Optimization, standardization and development of a new functional assay for the evaluation of malaria immunity using the antibody dependant respiratory burst (ADRB) of cell effectors detected by chemiluminescence
Objectives
1. To optimize and standardize a ‘new’ functional assay, the Antibody Dependant Respiratory Burst (ADRB) assay, detected by chemiluminescence.
2. To use this assay as a tool to evaluate the level of malaria immunity in different endemic populations.