Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MLW)

Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MLW)

Consultation date: 24 October 2014

Malaria elimination strategy

The Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MLW) is an internationally leading health research institution led by Malawian & international scientists, pursuing scientific excellence and improving the health of people in sub-Saharan Africa. MLW is affiliated with the Liverpool School of Tropical Medicine (LSTM) and the College of Medicine (COM) and is based in Blantyre with field research sites around urban Blantyre, Thyolo and Chikhwawa. MLW aims to conduct high quality research relevant to health in sub-Saharan Africa.

Blantyre remains unique as a research centre on cerebral malaria, combining MRI diagnostics, pathology, opthalmology with excellent lab facilities to explore the pathogenesis and management of cerebral malaria. In line with development in malaria control efforts the malaria theme research agenda has expanded to include research on optimizing case management of uncomplicated malaria and prevention in control programmes.

Malaria research projects include assessing pathogenesis (mechanisms of severe disease, parasite virulence, malaria retinopathy, co-infection and the host response), optimizing case management (severe anaemia, uncomplicated malaria in programmatic settings, drug interactions and safety and PK/PD) and monitoring and evaluation methods (sub-national tools for facility and community-level M&E of control progress, decision management systems, molecular epidemiology and entomology surveys).

Leading 10 project(s)