Malaria Infectious Reservoir and Genomics (MIRaGe)

Malaria Infectious Reservoir and Genomics (MIRaGe)

Objectives

How Plasmodium falciparum malaria parasites survive during the dry season in asymptomatic chronic infections is not known. The MIRaGe project regularly collects blood samples all year round from participants in the URR (Eastern Gambia) to perform a wide range of assays, including parasite whole genome sequencing, RNA-seq, qPCR and membrane feeding assays. Results will enable us to understand how P. falciparum parasites establish a long-term infection.

PI Institution(s)

Funding source(s)

Key facts

  • Funding information
    MRC UK/LSHTM West African Fellowship
    Country
    • Gambia

MESA tags

  • Methodology
    Basic science
    Theme(s)
    Asymptomatic reservoir, Parasite genetic diversity