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Abstract

The objective of this study is to evaluate the impact of the administration of ivermectin on vectors transmitting malaria in order to determine the effectiveness of this drug as an innovative and additional tool in the integrated malaria control. It is expected that ivermectin help to overcome the important challenges posed by malaria vectors: (1) its mode of action is different from classes of insecticides currently used, bypassing the emergence of resistance to insecticides, (2) it is as a systemic drug, it is ingested by all biting mosquitoes, reaching also those with endo- and exofágico behavior, and (3) the drug's activity targets the main variable of vectorial capacity, which is the probability of mosquito daily survival. 

This study will allow the generation of more reliable evidence and will lead to increased experience of the research group in this type of methodology.