Genomic-based diagnostics for elimination and eradication of Plasmodium

Genomic-based diagnostics for elimination and eradication of Plasmodium

Objectives

Our goal is to understand threats to the malaria elimination/eradication agenda. As effective control measures are deployed, parasite populations change due to selective pressures (e.g. as applied by drugs and vaccines) and to local population bottlenecks. In the past years, we have developed population biology tools that permit effective, efficient monitoring of parasite transmission and population dynamics through simple genetic testing of parasites sampled from the population. We propose to develop and validate those methods to measure changes in response to intervention, and to discover genes associated with key parasite properties important to control.

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Partner(s)

Key facts

  • Dates
    Nov 2012 to Jul 2016
    Country
    • Mozambique
    • Zambia
    • Senegal