Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia

Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia

Objectives

  1. To determine the effectiveness of SP for IPTp as evaluated by pregnancy outcomes following IPTp;
  2. To determine the efficacy of SP for IPTp in clearing peripheral parasitemia in asymptomatic pregnant women;
  3. To characterize baseline resistance of P. falciparum to SP in select locations in Zambia using molecular markers;
  4. To assess the relationship of therapeutic efficacy and SP for IPTp effectiveness with molecular markers for SP resistance.

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Key facts

  • Dates
    Jan 2010 to May 2011
    Funding amount
    $100,000
    Country
    • Zambia

MESA tags

  • Methodology
    Operational research
    Theme(s)
    Drug-based strategies, Vulnerable populations