Objectives

1. To examine the frequency of fast-intermediate-slow CYP2D6 metabolism of a single dose of dextromethorphan among patients who relapsed after directly observed primaquine therapy compared to those who did not relapse.

2. To compare the CYP2D6 phenotype with CYP2D6 genotype, to compare primaquine pharmacokinetics by phenotype and genotype status

 

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Partner(s)