Combination of malaria vector control interventions in pyrethroid resistance area in Benin: a cluster randomised controlled trial

Combination of malaria vector control interventions in pyrethroid resistance area in Benin: a cluster randomised controlled trial

Objectives

To evaluate the efficacy of non-pyrethroid IRS on malaria transmission and malaria morbidity, its effects on the development of resistance and on the behaviour of Anopheles mosquitoes, and the involvement of communities in such a strategy.

Specific objectives are:

  1. To identify a carbamate or organophosphate insecticide for use against populations of pyrethroid-resistant An. gambiae to preserve the efficacy of ITNs, LLINs and IRS.
  2. To evaluate the impact of a vector control strategy based on non-pyrethroid IRS on malaria morbidity and malaria transmission.

  3. To evaluate the impact of a vector control strategy based on non-pyrethroid IRS on the evolution of pyrethroid resistance and on the behaviour and population dynamics of An. gambiae.

  4. To assess the perception and the adherence of communities to this strategy and its feasibility on a national scale.

  5. To identify the different levels of susceptibility/resistance of An. gambiae to insecticides in Benin.

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Key facts

  • Funding amount
    $300,000
    Country
    • Benin

MESA tags

  • Methodology
    Entomology, Operational research
    Theme(s)
    Impact of interventions, Insecticide resistance, Tools for elimination