Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR

Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR

PI Institution(s)

Principal Investigator (PI)

Partner(s)

Abstract

This trial is evaluating the use of insect repellent (20% diethyltoluamide) to reduce incidence of malaria, Japanese Encephalitis and Dengue. The investigators will recruit up to 1000 households from 100 villages in rural Laos. In each house the investigators shall recruit up to 5 individuals. Half of households will be randomised to repellent, half to a placebo. All individuals will be provided with insecticide treated bed nets for use at night. All household occupants will be followed for 7 months to record malaria cases by Rapid Diagnostic Test every month. Blood spots will be collected at start and end of study to measure Japanese Encephalitis and Dengue. All positive cases will be promptly treated. Outcome will be reduction in number of malaria cases (primary outcome) and Dengue/Japanese Encephalitis (secondary outcomes).

http://ClinicalTrials.gov/show/NCT00938379

Key facts

  • Dates
    Jul 2009 to Jun 2011
    Country
    • Lao People's Democratic Republic

MESA tags

  • Methodology
    Entomology, Product development & clinical research
    Theme(s)
    Impact of interventions, Tools for elimination