Objectives

1. To assess a higher dose of Dihydroartemisinin-piperaquine (DHA-PPQ) in young kids for safety, particularly cardiac safety.

Currently the recommended dose range of DHA-PPQ is so narrow it does not allow an easy age-based dose regimen. This study aims to add valuable safety data and will likely contribute to the determination of safe dose regimens for MDA strategies. Findings from this DHA-PPQ dose-ranging study in children will be very informative for MDA campaigns and other strategies aiming to reduce malaria transmission using this drug.

Link: http://www.mlw.medcol.mw/index.php/malaria-theme-project-profiles.html

PI Institution(s)

Principal Investigator (PI)

Funding source(s)

Partner(s)